The Rev. Howard B. Warren, Jr., affectionately known as "God's Glorious Gadfly," was born September 7, 1934, in St. Louis, Missouri. He was a graduate of McCormick Theological Seminary; and he held degrees from Missouri Valley College and Union Theological Seminary (New York). He also held a masters degree from the School of Social Work at Hunter College. Ordained by the Presbytery of Kansas City in 1965, Warren served Presbyterian churches for 25 years. His pastorates were in Milford, Penn.; Vernon, Fayetteville and Huntington, New York; Pontiac, Michigan; and Orchard Park, Indiana.
In 1987, Howard came out to the Presbytery of Detroit as a person with AIDS and a gay man. Active in Presbyterians for Lesbian and Gay Concerns (now More Light Presbyterians), he was a founder of Presbyterians Act Up, was active with the Presbyterian AIDS Network and was a founding supporter of That All May Freely Serve.
From the time of his diagnosis with HIV/AIDS in 1987, until he required hospital and nursing home care in 2001, he was an advocate and caregiver for persons with HIV/AIDS and their families, friends and partners. He served as the director of pastoral care at the Damien Center in Indianapolis from 1989 to 1999, a care site for HIV/AIDS patients that was established by the Episcopal Diocese of Indianapolis and the Roman Catholic Archdiocese of Indianapolis.